TY - GEN AU - Gillardon,F AU - Schmid,R AU - Draheim,H TI - Parkinson's disease-linked leucine-rich repeat kinase 2(R1441G) mutation increases proinflammatory cytokine release from activated primary microglial cells and resultant neurotoxicity SN - 1873-7544 PY - 2012///0720 KW - Animals KW - Blotting, Western KW - Cells, Cultured KW - Chemokines KW - metabolism KW - Culture Media, Conditioned KW - Cytokines KW - biosynthesis KW - Electrophoresis, Polyacrylamide Gel KW - Gene Expression Profiling KW - Humans KW - Immunohistochemistry KW - Inflammation KW - genetics KW - Interferon-gamma KW - pharmacology KW - Leucine-Rich Repeat Serine-Threonine Protein Kinase-2 KW - Lipopolysaccharides KW - Macrophage Activation KW - physiology KW - Mice KW - Mice, Transgenic KW - Microglia KW - Mutation KW - Neurons KW - Neurotoxicity Syndromes KW - Parkinson Disease KW - Protein Serine-Threonine Kinases KW - Signal Transduction KW - drug effects KW - Toll-Like Receptor 4 N1 - Publication Type: Journal Article UR - https://doi.org/10.1016/j.neuroscience.2012.02.001 ER -