Gillardon, F <br/><br/>
Parkinson's disease-linked leucine-rich repeat kinase 2(R1441G) mutation increases proinflammatory cytokine release from activated primary microglial cells and resultant neurotoxicity.  [electronic resource] 

 -  Neuroscience  Apr 2012 
 - 41-8 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1873-7544 
<br/><br/><label>Standard No.: </label>10.1016/j.neuroscience.2012.02.001  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Blotting, Western<br/>Cells, Cultured<br/>Chemokines--metabolism<br/>Culture Media, Conditioned<br/>Cytokines--biosynthesis<br/>Electrophoresis, Polyacrylamide Gel<br/>Gene Expression Profiling<br/>Humans<br/>Immunohistochemistry<br/>Inflammation--genetics<br/>Interferon-gamma--pharmacology<br/>Leucine-Rich Repeat Serine-Threonine Protein Kinase-2<br/>Lipopolysaccharides--pharmacology<br/>Macrophage Activation--physiology<br/>Mice<br/>Mice, Transgenic<br/>Microglia--metabolism<br/>Mutation--physiology<br/>Neurons--physiology<br/>Neurotoxicity Syndromes--genetics<br/>Parkinson Disease--genetics<br/>Protein Serine-Threonine Kinases--genetics<br/>Signal Transduction--drug effects<br/>Toll-Like Receptor 4--biosynthesis