TY  - GEN
AU  - Liu,Xingrong
AU  - Ding,Xiao
AU  - Deshmukh,Gauri
AU  - Liederer,Bianca M
AU  - Hop,Cornelis E C A
TI  - Use of the cassette-dosing approach to assess brain penetration in drug discovery
SN  - 1521-009X
PY  - 2012///0823
KW  - ATP Binding Cassette Transporter, Subfamily B
KW  - genetics
KW  - ATP Binding Cassette Transporter, Subfamily G, Member 2
KW  - ATP-Binding Cassette Transporters
KW  - Animals
KW  - Biological Transport
KW  - Brain
KW  - metabolism
KW  - Chromatography, High Pressure Liquid
KW  - Dose-Response Relationship, Drug
KW  - Drug Discovery
KW  - methods
KW  - Drug Interactions
KW  - Injections, Subcutaneous
KW  - Limit of Detection
KW  - Mice
KW  - Mice, Knockout
KW  - Models, Biological
KW  - Pharmaceutical Preparations
KW  - administration & dosage
KW  - Substrate Specificity
KW  - Tandem Mass Spectrometry
KW  - ATP-Binding Cassette Sub-Family B Member 4
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1124/dmd.111.044420
ER  -