Tsubaki, Masanobu

Reduction of metastasis, cell invasion, and adhesion in mouse osteosarcoma by YM529/ONO-5920-induced blockade of the Ras/MEK/ERK and Ras/PI3K/Akt pathway. [electronic resource] - Toxicology and applied pharmacology Mar 2012 - 402-10 p. digital

Publication Type: Journal Article

1096-0333

10.1016/j.taap.2012.01.024 doi


Animals
Cell Adhesion--drug effects
Cell Line, Tumor
Cell Movement--drug effects
Diphosphonates--pharmacology
Extracellular Signal-Regulated MAP Kinases--antagonists & inhibitors
Gene Expression Regulation, Neoplastic--drug effects
Imidazoles--pharmacology
Male
Matrix Metalloproteinases--genetics
Mice
Mice, Inbred C3H
Mitogen-Activated Protein Kinase Kinases--antagonists & inhibitors
Neoplasm Invasiveness--prevention & control
Neoplasm Metastasis--prevention & control
Osteosarcoma--drug therapy
Phosphoinositide-3 Kinase Inhibitors
Proto-Oncogene Proteins c-akt--antagonists & inhibitors
RNA, Messenger--metabolism
ras Proteins--antagonists & inhibitors