Remote ischemic postconditioning protects the brain from global cerebral ischemia/reperfusion injury by up-regulating endothelial nitric oxide synthase through the PI3K/Akt pathway. [electronic resource]
- Brain research Mar 2012
- 92-102 p. digital
Publication Type: Journal Article
1872-6240
10.1016/j.brainres.2012.01.033 doi
Analysis of Variance Animals Avoidance Learning--drug effects Brain--blood supply Brain Infarction--prevention & control Brain Ischemia--pathology Cell Death--physiology Chromones--pharmacology Disease Models, Animal Enzyme Inhibitors--pharmacology Gene Expression Regulation--physiology In Situ Nick-End Labeling Ischemic Postconditioning--methods Male Maze Learning--physiology Morpholines--pharmacology NG-Nitroarginine Methyl Ester--pharmacology Nitric Oxide Synthase Type III--metabolism Nitroarginine--pharmacology Oncogene Protein v-akt--metabolism Phosphatidylinositol 3-Kinase--metabolism Rats Rats, Sprague-Dawley Reaction Time--drug effects Reperfusion Injury--pathology