Garcia-Marcos, Mikel

Functional characterization of the guanine nucleotide exchange factor (GEF) motif of GIV protein reveals a threshold effect in signaling. [electronic resource] - Proceedings of the National Academy of Sciences of the United States of America Feb 2012 - 1961-6 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1091-6490

10.1073/pnas.1120538109 doi


Amino Acid Motifs
Amino Acid Sequence
Cell Movement--drug effects
GTP-Binding Protein alpha Subunits, Gi-Go--metabolism
Guanine Nucleotide Exchange Factors--chemistry
HeLa Cells
Humans
Insulin--pharmacology
Lysophospholipids--pharmacology
Microfilament Proteins--chemistry
Models, Molecular
Molecular Sequence Data
Mutant Proteins--chemistry
Mutation--genetics
Protein Binding--drug effects
Proto-Oncogene Proteins c-akt--metabolism
Signal Transduction--drug effects
Stress Fibers--drug effects
Vesicular Transport Proteins--chemistry