Pereira, Luísa

Somatic mitochondrial DNA mutations in cancer escape purifying selection and high pathogenicity mutations lead to the oncocytic phenotype: pathogenicity analysis of reported somatic mtDNA mutations in tumors. [electronic resource] - BMC cancer Feb 2012 - 53 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review

1471-2407

10.1186/1471-2407-12-53 doi


DNA, Mitochondrial--genetics
Electron Transport Complex I--genetics
Humans
Mitochondrial Proteins--genetics
Mutation--genetics
Neoplasms--genetics
Phenotype
Phylogeny
Selection, Genetic