Somatic mitochondrial DNA mutations in cancer escape purifying selection and high pathogenicity mutations lead to the oncocytic phenotype: pathogenicity analysis of reported somatic mtDNA mutations in tumors. [electronic resource]
- BMC cancer Feb 2012
- 53 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
1471-2407
10.1186/1471-2407-12-53 doi
DNA, Mitochondrial--genetics Electron Transport Complex I--genetics Humans Mitochondrial Proteins--genetics Mutation--genetics Neoplasms--genetics Phenotype Phylogeny Selection, Genetic