mRNA for N-Bak, a neuron-specific BH3-only splice isoform of Bak, escapes nonsense-mediated decay and is translationally repressed in the neurons. [electronic resource]
- Cell death & disease Feb 2012
- e269 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
2041-4889
10.1038/cddis.2012.4 doi
5' Flanking Region--genetics Alternative Splicing Animals Apoptosis--drug effects Codon, Nonsense Cycloheximide--pharmacology Embryo, Mammalian Exons HeLa Cells Humans Mice Mitochondria--drug effects Neurons--cytology Primary Cell Culture Protein Biosynthesis--drug effects Protein Isoforms Protein Synthesis Inhibitors--pharmacology RNA, Messenger--biosynthesis Transfection bcl-2 Homologous Antagonist-Killer Protein--genetics