TY - GEN AU - Fujita,Akiko AU - Yoh,Keigyou AU - Shimohata,Homare AU - Morito,Naoki AU - Ojima,Masami AU - Okamura,Midori AU - Takahashi,Satoru AU - Yamagata,Kunihiro TI - A novel diabetes mellitus mouse model, MAFA-deficient and beta cell-specific MAFK-overexpressing hybrid transgenic mice, developed severe diabetic nephropathy and improved with TCV-116 (candesartan cilexetil) treatment SN - 1881-7122 PY - 2012///0522 KW - 8-Hydroxy-2'-Deoxyguanosine KW - Angiotensin II Type 1 Receptor Blockers KW - therapeutic use KW - Animals KW - Benzimidazoles KW - Biphenyl Compounds KW - Deoxyguanosine KW - analogs & derivatives KW - Diabetes Mellitus, Experimental KW - genetics KW - Diabetes Mellitus, Type 2 KW - physiopathology KW - Diabetic Nephropathies KW - drug therapy KW - Disease Models, Animal KW - Enzyme-Linked Immunosorbent Assay KW - Humans KW - Kidney KW - pathology KW - Maf Transcription Factors, Large KW - MafK Transcription Factor KW - Male KW - Mice KW - Mice, Transgenic KW - Nephrectomy KW - Tetrazoles N1 - Publication Type: Journal Article UR - https://doi.org/10.1538/expanim.61.49 ER -