Gherezghiher, Teshome B <br/><br/>
The naphthol selective estrogen receptor modulator (SERM), LY2066948, is oxidized to an o-quinone analogous to the naphthol equine estrogen, equilenin.  [electronic resource] 

 -  Chemico-biological interactions  Mar 2012 
 - 1-10 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, N.I.H., Extramural 
<br/><br/><label>ISSN: </label>1872-7786 
<br/><br/><label>Standard No.: </label>10.1016/j.cbi.2012.01.004  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Aryl Hydrocarbon Hydroxylases--metabolism<br/>Cell Line, Tumor<br/>Cell Survival--drug effects<br/>Cytochrome P-450 CYP1B1<br/>Cytochrome P-450 CYP3A--metabolism<br/>Dose-Response Relationship, Drug<br/>Equilenin--analogs & derivatives<br/>Female<br/>Half-Life<br/>Inhibitory Concentration 50<br/>Kinetics<br/>Magnetic Resonance Spectroscopy<br/>Microsomes, Liver<br/>Naphthalenes--chemistry<br/>Oxidation-Reduction<br/>Piperidines--chemistry<br/>Quinones--chemistry<br/>Rats<br/>Rats, Sprague-Dawley<br/>Selective Estrogen Receptor Modulators--chemistry<br/>Tandem Mass Spectrometry