TY  - GEN
AU  - De Marino,Simona
AU  - Ummarino,Raffaella
AU  - D'Auria,Maria Valeria
AU  - Chini,Maria Giovanna
AU  - Bifulco,Giuseppe
AU  - D'Amore,Claudio
AU  - Renga,Barbara
AU  - Mencarelli,Andrea
AU  - Petek,Sylvain
AU  - Fiorucci,Stefano
AU  - Zampella,Angela
TI  - 4-Methylenesterols from Theonella swinhoei sponge are natural pregnane-X-receptor agonists and farnesoid-X-receptor antagonists that modulate innate immunity
SN  - 1878-5867
PY  - 2012///0814
KW  - Animals
KW  - Binding Sites
KW  - CD4-Positive T-Lymphocytes
KW  - drug effects
KW  - Cholesterol
KW  - analogs & derivatives
KW  - Cytokines
KW  - genetics
KW  - Gene Expression
KW  - Gene Expression Profiling
KW  - Hep G2 Cells
KW  - Humans
KW  - Isomerism
KW  - Liver
KW  - Mice
KW  - Mice, Inbred C57BL
KW  - Mice, Knockout
KW  - Models, Molecular
KW  - Molecular Structure
KW  - Monocytes
KW  - Pregnane X Receptor
KW  - Protein Binding
KW  - Protein Structure, Tertiary
KW  - Receptors, Cytoplasmic and Nuclear
KW  - antagonists & inhibitors
KW  - Receptors, Steroid
KW  - agonists
KW  - Reverse Transcriptase Polymerase Chain Reaction
KW  - Sterols
KW  - chemistry
KW  - T-Lymphocytes, Regulatory
KW  - Theonella
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1016/j.steroids.2012.01.006
ER  -