De Marino, Simona <br/><br/>
4-Methylenesterols from Theonella swinhoei sponge are natural pregnane-X-receptor agonists and farnesoid-X-receptor antagonists that modulate innate immunity.  [electronic resource] 

 -  Steroids  Apr 2012 
 - 484-95 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1878-5867 
<br/><br/><label>Standard No.: </label>10.1016/j.steroids.2012.01.006  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Binding Sites<br/>CD4-Positive T-Lymphocytes--drug effects<br/>Cholesterol--analogs & derivatives<br/>Cytokines--genetics<br/>Gene Expression--drug effects<br/>Gene Expression Profiling<br/>Hep G2 Cells<br/>Humans<br/>Isomerism<br/>Liver--drug effects<br/>Mice<br/>Mice, Inbred C57BL<br/>Mice, Knockout<br/>Models, Molecular<br/>Molecular Structure<br/>Monocytes--drug effects<br/>Pregnane X Receptor<br/>Protein Binding<br/>Protein Structure, Tertiary<br/>Receptors, Cytoplasmic and Nuclear--antagonists & inhibitors<br/>Receptors, Steroid--agonists<br/>Reverse Transcriptase Polymerase Chain Reaction<br/>Sterols--chemistry<br/>T-Lymphocytes, Regulatory--drug effects<br/>Theonella--chemistry