TY  - GEN
AU  - Prahallad,Anirudh
AU  - Sun,Chong
AU  - Huang,Sidong
AU  - Di Nicolantonio,Federica
AU  - Salazar,Ramon
AU  - Zecchin,Davide
AU  - Beijersbergen,Roderick L
AU  - Bardelli,Alberto
AU  - Bernards,René
TI  - Unresponsiveness of colon cancer to BRAF(V600E) inhibition through feedback activation of EGFR
SN  - 1476-4687
PY  - 2012///0418
KW  - Animals
KW  - Antibodies, Monoclonal
KW  - pharmacology
KW  - Antibodies, Monoclonal, Humanized
KW  - Antineoplastic Agents
KW  - Apoptosis
KW  - drug effects
KW  - Cell Line, Tumor
KW  - Cell Proliferation
KW  - Cetuximab
KW  - Colorectal Neoplasms
KW  - drug therapy
KW  - Drug Resistance, Neoplasm
KW  - Drug Synergism
KW  - Enzyme Activation
KW  - ErbB Receptors
KW  - agonists
KW  - Erlotinib Hydrochloride
KW  - Feedback, Physiological
KW  - Female
KW  - Gefitinib
KW  - HEK293 Cells
KW  - Humans
KW  - Indoles
KW  - Melanoma
KW  - Mice
KW  - Protein Kinase Inhibitors
KW  - Proto-Oncogene Proteins B-raf
KW  - antagonists & inhibitors
KW  - Quinazolines
KW  - RNA Interference
KW  - Sulfonamides
KW  - Vemurafenib
KW  - Xenograft Model Antitumor Assays
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1038/nature10868
ER  -