Prahallad, Anirudh <br/><br/>
Unresponsiveness of colon cancer to BRAF(V600E) inhibition through feedback activation of EGFR.  [electronic resource] 

 -  Nature  Jan 2012 
 - 100-3 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1476-4687 
<br/><br/><label>Standard No.: </label>10.1038/nature10868  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Antibodies, Monoclonal--pharmacology<br/>Antibodies, Monoclonal, Humanized<br/>Antineoplastic Agents--pharmacology<br/>Apoptosis--drug effects<br/>Cell Line, Tumor<br/>Cell Proliferation--drug effects<br/>Cetuximab<br/>Colorectal Neoplasms--drug therapy<br/>Drug Resistance, Neoplasm--drug effects<br/>Drug Synergism<br/>Enzyme Activation--drug effects<br/>ErbB Receptors--agonists<br/>Erlotinib Hydrochloride<br/>Feedback, Physiological--drug effects<br/>Female<br/>Gefitinib<br/>HEK293 Cells<br/>Humans<br/>Indoles--pharmacology<br/>Melanoma--drug therapy<br/>Mice<br/>Protein Kinase Inhibitors--pharmacology<br/>Proto-Oncogene Proteins B-raf--antagonists & inhibitors<br/>Quinazolines--pharmacology<br/>RNA Interference<br/>Sulfonamides--pharmacology<br/>Vemurafenib<br/>Xenograft Model Antitumor Assays