A novel role for BDNF-TrkB in the regulation of chemotherapy resistance in head and neck squamous cell carcinoma. [electronic resource]
- PloS one 2012
- e30246 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1932-6203
10.1371/journal.pone.0030246 doi
ATP Binding Cassette Transporter, Subfamily B, Member 1--genetics Antineoplastic Agents--pharmacology Apoptosis Regulatory Proteins--genetics Bcl-2-Like Protein 11 Blotting, Western Brain-Derived Neurotrophic Factor--genetics Carcinoma, Squamous Cell--metabolism Cell Line, Tumor Cell Proliferation--drug effects Cisplatin--pharmacology Drug Resistance, Neoplasm--genetics Enzyme-Linked Immunosorbent Assay Head and Neck Neoplasms--metabolism Humans Immunohistochemistry Membrane Proteins--genetics Proto-Oncogene Proteins--genetics Receptor, trkB--genetics Reverse Transcriptase Polymerase Chain Reaction Squamous Cell Carcinoma of Head and Neck X-Linked Inhibitor of Apoptosis Protein--genetics