TY - GEN AU - Nagaraj,Ram H AU - Panda,Alok Kumar AU - Shanthakumar,Shilpa AU - Santhoshkumar,Puttur AU - Pasupuleti,NagaRekha AU - Wang,Benlian AU - Biswas,Ashis TI - Hydroimidazolone modification of the conserved Arg12 in small heat shock proteins: studies on the structure and chaperone function using mutant mimics SN - 1932-6203 PY - 2012///0611 KW - Amino Acid Sequence KW - Arginine KW - chemistry KW - Binding Sites KW - genetics KW - Circular Dichroism KW - Electrophoresis, Polyacrylamide Gel KW - HSP27 Heat-Shock Proteins KW - Imidazoles KW - Kinetics KW - Molecular Chaperones KW - Molecular Sequence Data KW - Molecular Structure KW - Mutation KW - Protein Binding KW - drug effects KW - Protein Structure, Secondary KW - Protein Structure, Tertiary KW - Pyruvaldehyde KW - pharmacology KW - Recombinant Proteins KW - Sequence Homology, Amino Acid KW - Spectrometry, Fluorescence KW - Thermodynamics KW - alpha-Crystallin A Chain KW - alpha-Crystallin B Chain N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1371/journal.pone.0030257 ER -