Bisphosphonate-induced osteonecrosis of the jaw in a rat model arises first after the bone has become exposed. No primary necrosis in unexposed bone. [electronic resource]
- Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology Jul 2012
- 494-9 p. digital
Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
1600-0714
10.1111/j.1600-0714.2011.01125.x doi
Alendronate--administration & dosage Animals Anti-Inflammatory Agents--administration & dosage Bisphosphonate-Associated Osteonecrosis of the Jaw--etiology Bone Density Conservation Agents--administration & dosage Cell Death--physiology Cell Survival--drug effects Dexamethasone--administration & dosage Disease Models, Animal Gingival Diseases--etiology Gingivectomy--methods Glucocorticoids--administration & dosage L-Lactate Dehydrogenase--analysis Male Maxilla--surgery Molar--surgery Oral Ulcer--etiology Osteocytes--drug effects Random Allocation Rats Rats, Sprague-Dawley Tooth Extraction--adverse effects Tooth Socket--drug effects Wound Healing--drug effects