TY - GEN AU - Onoue,Satomi AU - Inoue,Ryo AU - Taniguchi,Chika AU - Kawabata,Yohei AU - Yamashita,Kazuhiro AU - Wada,Koichi AU - Yamauchi,Yukinori AU - Yamada,Shizuo TI - Improved dissolution and pharmacokinetic behavior of dipyridamole formulation with microenvironmental pH-modifier under hypochlorhydria SN - 1873-3476 PY - 2012///0622 KW - Achlorhydria KW - chemically induced KW - Administration, Oral KW - Animals KW - Area Under Curve KW - Biological Availability KW - Chemistry, Pharmaceutical KW - Chromatography, Liquid KW - Crystallization KW - Crystallography, X-Ray KW - Dipyridamole KW - administration & dosage KW - Disease Models, Animal KW - Drug Compounding KW - Drug Stability KW - Fumarates KW - chemistry KW - Half-Life KW - Hydrogen-Ion Concentration KW - Male KW - Metabolic Clearance Rate KW - Microscopy, Electron, Scanning KW - Omeprazole KW - Phosphodiesterase Inhibitors KW - Powder Diffraction KW - Rats KW - Rats, Sprague-Dawley KW - Solubility KW - Spectrometry, Mass, Electrospray Ionization KW - Technology, Pharmaceutical KW - methods N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1016/j.ijpharm.2012.01.014 ER -