TY  - GEN
AU  - Fujimaki,Shun
AU  - Matsuda,Yasunobu
AU  - Wakai,Toshifumi
AU  - Sanpei,Ayumi
AU  - Kubota,Masayuki
AU  - Takamura,Masaaki
AU  - Yamagiwa,Satoshi
AU  - Yano,Masahiko
AU  - Ohkoshi,Shogo
AU  - Aoyagi,Yutaka
TI  - Blockade of ataxia telangiectasia mutated sensitizes hepatoma cell lines to sorafenib by interfering with Akt signaling
SN  - 1872-7980
PY  - 2012///0427
KW  - Antineoplastic Agents
KW  - therapeutic use
KW  - Ataxia Telangiectasia Mutated Proteins
KW  - Benzenesulfonates
KW  - Caffeine
KW  - Carcinoma, Hepatocellular
KW  - drug therapy
KW  - Cell Cycle Proteins
KW  - antagonists & inhibitors
KW  - Cell Line, Tumor
KW  - DNA-Binding Proteins
KW  - Drug Screening Assays, Antitumor
KW  - Drug Synergism
KW  - Humans
KW  - Liver Neoplasms
KW  - Niacinamide
KW  - analogs & derivatives
KW  - Phenylurea Compounds
KW  - Protein Serine-Threonine Kinases
KW  - Proto-Oncogene Proteins c-akt
KW  - metabolism
KW  - Pyridines
KW  - RNA, Small Interfering
KW  - Signal Transduction
KW  - drug effects
KW  - Sorafenib
KW  - Tumor Suppressor Proteins
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1016/j.canlet.2011.12.043
ER  -