Tischner, Denise

Defective cell death signalling along the Bcl-2 regulated apoptosis pathway compromises Treg cell development and limits their functionality in mice. [electronic resource] - Journal of autoimmunity Feb 2012 - 59-69 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1095-9157

10.1016/j.jaut.2011.12.008 doi


Animals
Antineoplastic Agents--pharmacology
Apoptosis--genetics
Apoptosis Regulatory Proteins--genetics
Bcl-2-Like Protein 11
CD4-Positive T-Lymphocytes--metabolism
Cell Survival--drug effects
Cells, Cultured
Etoposide--pharmacology
Female
Flow Cytometry
Forkhead Transcription Factors--genetics
Gene Expression Profiling
Green Fluorescent Proteins--genetics
Inflammatory Bowel Diseases--genetics
Male
Membrane Proteins--genetics
Mice
Mice, Inbred C57BL
Mice, Knockout
Mice, Transgenic
Proto-Oncogene Proteins--genetics
Proto-Oncogene Proteins c-bcl-2--genetics
Reverse Transcriptase Polymerase Chain Reaction
Signal Transduction--genetics
T-Lymphocytes, Regulatory--metabolism
Thymus Gland--cytology