TY  - GEN
AU  - Chu,Seung Y
AU  - Horton,Holly M
AU  - Pong,Erik
AU  - Leung,Irene W L
AU  - Chen,Hsing
AU  - Nguyen,Duc-Hanh
AU  - Bautista,Cristina
AU  - Muchhal,Umesh S
AU  - Bernett,Matthew J
AU  - Moore,Gregory L
AU  - Szymkowski,David E
AU  - Desjarlais,John R
TI  - Reduction of total IgE by targeted coengagement of IgE B-cell receptor and FcγRIIb with Fc-engineered antibody
SN  - 1097-6825
PY  - 2012///0709
KW  - Animals
KW  - Anti-Allergic Agents
KW  - pharmacology
KW  - Antibodies, Anti-Idiotypic
KW  - blood
KW  - Antibodies, Monoclonal, Humanized
KW  - Antibody Affinity
KW  - immunology
KW  - B-Lymphocytes
KW  - drug effects
KW  - Humans
KW  - Immunoglobulin E
KW  - biosynthesis
KW  - Immunoglobulin Fc Fragments
KW  - genetics
KW  - Immunoglobulin G
KW  - Immunoglobulin M
KW  - Leukocytes, Mononuclear
KW  - metabolism
KW  - Lymphocyte Activation
KW  - Mice
KW  - Mice, Inbred C57BL
KW  - Mice, Knockout
KW  - Mice, SCID
KW  - Omalizumab
KW  - Protein Binding
KW  - Receptors, Antigen, B-Cell
KW  - antagonists & inhibitors
KW  - Receptors, IgE
KW  - Receptors, IgG
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1016/j.jaci.2011.11.029
ER  -