Elevation in body temperature to fever range enhances and prolongs subsequent responsiveness of macrophages to endotoxin challenge. [electronic resource]
- PloS one 2012
- e30077 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural
1932-6203
10.1371/journal.pone.0030077 doi
Animals Body Temperature--drug effects Female Fever--complications Gene Expression Regulation--drug effects HSP70 Heat-Shock Proteins--metabolism Hot Temperature Inflammation--complications Inflammation Mediators--metabolism Interferon-gamma--pharmacology Lipopolysaccharides--pharmacology Macrophage Activation--drug effects Macrophages, Peritoneal--drug effects Mice Mice, Inbred BALB C NF-kappa B--metabolism Tumor Necrosis Factor-alpha--biosynthesis