TY  - GEN
AU  - Astanehe,A
AU  - Finkbeiner,M R
AU  - Krzywinski,M
AU  - Fotovati,A
AU  - Dhillon,J
AU  - Berquin,I M
AU  - Mills,G B
AU  - Marra,M A
AU  - Dunn,S E
TI  - MKNK1 is a YB-1 target gene responsible for imparting trastuzumab resistance and can be blocked by RSK inhibition
SN  - 1476-5594
PY  - 2012///1213
KW  - Antibodies, Monoclonal, Humanized
KW  - pharmacology
KW  - Antineoplastic Agents
KW  - Apoptosis
KW  - Base Sequence
KW  - Breast Neoplasms
KW  - drug therapy
KW  - Cell Line, Tumor
KW  - Chromatin Immunoprecipitation
KW  - Drug Resistance, Neoplasm
KW  - genetics
KW  - Female
KW  - Gene Expression Regulation, Neoplastic
KW  - Gene Knockdown Techniques
KW  - Humans
KW  - Intracellular Signaling Peptides and Proteins
KW  - Phosphorylation
KW  - Protein Array Analysis
KW  - Protein Processing, Post-Translational
KW  - Protein Serine-Threonine Kinases
KW  - Pteridines
KW  - Ribosomal Protein S6 Kinases, 90-kDa
KW  - antagonists & inhibitors
KW  - Sequence Analysis, DNA
KW  - Transcription, Genetic
KW  - Trastuzumab
KW  - Y-Box-Binding Protein 1
KW  - metabolism
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1038/onc.2011.617
ER  -