TY  - GEN
AU  - Keravis,Thérèse
AU  - Monneaux,Fanny
AU  - Yougbaré,Issaka
AU  - Gazi,Lucien
AU  - Bourguignon,Jean-Jacques
AU  - Muller,Sylviane
AU  - Lugnier,Claire
TI  - Disease progression in MRL/lpr lupus-prone mice is reduced by NCS 613, a specific cyclic nucleotide phosphodiesterase type 4 (PDE4) inhibitor
SN  - 1932-6203
PY  - 2012///0514
KW  - Adenine
KW  - analogs & derivatives
KW  - Animals
KW  - Cyclic AMP
KW  - metabolism
KW  - Cyclic Nucleotide Phosphodiesterases, Type 4
KW  - chemistry
KW  - Disease Progression
KW  - Female
KW  - Humans
KW  - Isoenzymes
KW  - Kidney
KW  - cytology
KW  - Lipopolysaccharides
KW  - pharmacology
KW  - Lupus Erythematosus, Systemic
KW  - drug therapy
KW  - Mice
KW  - Mice, Inbred CBA
KW  - Mice, Inbred MRL lpr
KW  - Pentoxifylline
KW  - therapeutic use
KW  - Phosphodiesterase 4 Inhibitors
KW  - Proteinuria
KW  - Survival Rate
KW  - Tumor Necrosis Factor-alpha
KW  - Xanthines
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1371/journal.pone.0028899
ER  -