TY - GEN AU - Dumont,Jennifer A AU - Liu,Tongyao AU - Low,Susan C AU - Zhang,Xin AU - Kamphaus,George AU - Sakorafas,Paul AU - Fraley,Cara AU - Drager,Douglas AU - Reidy,Thomas AU - McCue,Justin AU - Franck,Helen W G AU - Merricks,Elizabeth P AU - Nichols,Timothy C AU - Bitonti,Alan J AU - Pierce,Glenn F AU - Jiang,Haiyan TI - Prolonged activity of a recombinant factor VIII-Fc fusion protein in hemophilia A mice and dogs SN - 1528-0020 PY - 2012///0525 KW - Animals KW - Coagulants KW - pharmacokinetics KW - Disease Models, Animal KW - Dog Diseases KW - drug therapy KW - Dogs KW - Factor VIII KW - chemistry KW - HEK293 Cells KW - Half-Life KW - Hemophilia A KW - Histocompatibility Antigens Class I KW - Humans KW - Mice KW - Mice, Inbred C57BL KW - Mice, Knockout KW - Mice, Transgenic KW - Receptors, Fc KW - Recombinant Fusion Proteins KW - Whole Blood Coagulation Time N1 - Publication Type: Evaluation Study; Journal Article UR - https://doi.org/10.1182/blood-2011-08-367813 ER -