TY  - GEN
AU  - Hayes,D Neil
AU  - Lucas,Amy S
AU  - Tanvetyanon,Tawee
AU  - Krzyzanowska,Monika K
AU  - Chung,Christine H
AU  - Murphy,Barbara A
AU  - Gilbert,Jill
AU  - Mehra,Ranee
AU  - Moore,Dominic T
AU  - Sheikh,Arif
AU  - Hoskins,Janelle
AU  - Hayward,Michele C
AU  - Zhao,Ni
AU  - O'Connor,Wendi
AU  - Weck,Karen E
AU  - Cohen,Roger B
AU  - Cohen,Ezra E W
TI  - Phase II efficacy and pharmacogenomic study of Selumetinib (AZD6244; ARRY-142886) in iodine-131 refractory papillary thyroid carcinoma with or without follicular elements
SN  - 1557-3265
PY  - 2012///0823
KW  - Adenocarcinoma, Follicular
KW  - drug therapy
KW  - Adult
KW  - Aged
KW  - Aged, 80 and over
KW  - Benzimidazoles
KW  - adverse effects
KW  - Carcinoma
KW  - Carcinoma, Papillary
KW  - Diarrhea
KW  - chemically induced
KW  - Exanthema
KW  - Fatigue
KW  - Female
KW  - Genotype
KW  - Humans
KW  - Iodine Radioisotopes
KW  - therapeutic use
KW  - Kaplan-Meier Estimate
KW  - Male
KW  - Middle Aged
KW  - Mutation
KW  - Pharmacogenetics
KW  - Proto-Oncogene Proteins B-raf
KW  - genetics
KW  - Thyroid Cancer, Papillary
KW  - Thyroid Neoplasms
KW  - Treatment Outcome
KW  - ras Proteins
N1  - Publication Type: Clinical Trial, Phase II; Journal Article; Multicenter Study; Research Support, N.I.H., Extramural
UR  - https://doi.org/10.1158/1078-0432.CCR-11-0563
ER  -