Onoue, Satomi <br/><br/>
Physicochemical and pharmacokinetic characterization of amorphous solid dispersion of tranilast with enhanced solubility in gastric fluid and improved oral bioavailability.  [electronic resource] 

 -  Drug metabolism and pharmacokinetics  2012 
 - 379-87 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1880-0920 
<br/><br/><label>Standard No.: </label>10.2133/dmpk.dmpk-11-rg-101  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Administration, Oral<br/>Animals<br/>Anti-Inflammatory Agents, Non-Steroidal--administration & dosage<br/>Area Under Curve<br/>Biological Availability<br/>Calorimetry, Differential Scanning<br/>Chemistry, Pharmaceutical<br/>Chromatography, Liquid<br/>Crystallization<br/>Crystallography, X-Ray<br/>Drug Stability<br/>Gastric Juice--chemistry<br/>Hydrogen-Ion Concentration<br/>Hydrophobic and Hydrophilic Interactions<br/>Injections, Intravenous<br/>Male<br/>Metabolic Clearance Rate<br/>Microscopy, Electron, Scanning<br/>Microscopy, Polarization<br/>Models, Biological<br/>Polymethacrylic Acids--chemistry<br/>Powder Diffraction<br/>Rats<br/>Rats, Sprague-Dawley<br/>Solubility<br/>Spectrometry, Mass, Electrospray Ionization<br/>Spectroscopy, Fourier Transform Infrared<br/>Spectroscopy, Near-Infrared<br/>Technology, Pharmaceutical--methods<br/>ortho-Aminobenzoates--administration & dosage