Mora-Pale, Mauricio

Trimer hydroxylated quinone derived from apocynin targets cysteine residues of p47phox preventing the activation of human vascular NADPH oxidase. [electronic resource] - Free radical biology & medicine Mar 2012 - 962-9 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural

1873-4596

10.1016/j.freeradbiomed.2011.12.015 doi


Acetophenones--chemistry
Animals
Biocatalysis
Cell Survival--drug effects
Cells, Cultured
Cysteine--chemistry
Endothelial Cells--drug effects
Enzyme Activation
Humans
Hydroxylation
Inhibitory Concentration 50
NADPH Oxidases--antagonists & inhibitors
PC12 Cells
Protein Binding
Quinones--chemical synthesis
Rats
Superoxides--metabolism