TY  - GEN
AU  - Deng,Chongyang
AU  - Liu,Juan
AU  - Wang,Guangcheng
AU  - Ma,Liang
AU  - Xie,Caifeng
AU  - Wang,Xuewei
AU  - Li,Xiuxia
AU  - Chen,Lijuan
TI  - A novel small molecule, (E)-5-(2,4-di-tert-butyl-6-((2,4-dioxothiazolidin-5-ylidene)methyl)phenyl)-5'-methyl-7,7'-dimethoxy-4,4'-bibenzo[d][1,3]dioxole-5,5'-dicarboxylate (7k), alleviates the development of D-galactosamine/lipopolysaccharide-induced acute liver failure by inhibiting macrophage infiltration and regulating cytokine expression
SN  - 1521-0103
PY  - 2012///0504
KW  - Animals
KW  - Anti-Inflammatory Agents, Non-Steroidal
KW  - toxicity
KW  - Cell Line
KW  - Cell Migration Inhibition
KW  - drug effects
KW  - Cell Movement
KW  - Cytokines
KW  - antagonists & inhibitors
KW  - Dioxoles
KW  - chemistry
KW  - Down-Regulation
KW  - Female
KW  - Galactosamine
KW  - Lipopolysaccharides
KW  - Liver Failure, Acute
KW  - chemically induced
KW  - Macrophages
KW  - Mice
KW  - Mice, Inbred BALB C
KW  - Thiazolidines
N1  - Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1124/jpet.111.189498
ER  -