TY - GEN AU - Berg,Randi K AU - Melchjorsen,Jesper AU - Rintahaka,Johanna AU - Diget,Elisabeth AU - Søby,Stine AU - Horan,Kristy A AU - Gorelick,Robert J AU - Matikainen,Sampsa AU - Larsen,Carsten S AU - Ostergaard,Lars AU - Paludan,Søren R AU - Mogensen,Trine H TI - Genomic HIV RNA induces innate immune responses through RIG-I-dependent sensing of secondary-structured RNA SN - 1932-6203 PY - 2012///0514 KW - Adaptor Proteins, Signal Transducing KW - metabolism KW - Animals KW - Cell Line, Tumor KW - DEAD Box Protein 58 KW - DEAD-box RNA Helicases KW - Genome, Viral KW - immunology KW - HIV-1 KW - genetics KW - Humans KW - Immunity, Innate KW - Interferon Regulatory Factors KW - Leukocytes, Mononuclear KW - cytology KW - Mice KW - Mice, Inbred C57BL KW - NF-kappa B KW - Nucleic Acid Conformation KW - Oligoribonucleotides KW - chemistry KW - Peroxisomes KW - Protein Transport KW - RNA, Viral KW - Receptors, Immunologic KW - Signal Transduction KW - Viral Proteins KW - p38 Mitogen-Activated Protein Kinases N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1371/journal.pone.0029291 ER -