Pascale, Silvia <br/><br/>
Aspirin-insensitive thromboxane biosynthesis in essential thrombocythemia is explained by accelerated renewal of the drug target.  [electronic resource] 

 -  Blood  Apr 2012 
 - 3595-603 p.  digital 
<br/><br/> Publication Type: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1528-0020 
<br/><br/><label>Standard No.: </label>10.1182/blood-2011-06-359224  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Acceleration<br/>Adult<br/>Aged<br/>Algorithms<br/>Anti-Inflammatory Agents, Non-Steroidal--therapeutic use<br/>Aspirin--administration & dosage<br/>Cross-Over Studies<br/>Cross-Sectional Studies--statistics & numerical data<br/>Cyclooxygenase 1--metabolism<br/>Cyclooxygenase 2--metabolism<br/>Drug Resistance--drug effects<br/>Female<br/>Half-Life<br/>Humans<br/>Male<br/>Metabolic Networks and Pathways--drug effects<br/>Middle Aged<br/>Molecular Targeted Therapy--methods<br/>Protein Biosynthesis--drug effects<br/>Thrombocythemia, Essential--drug therapy<br/>Thromboxane A2--biosynthesis