TY  - GEN
AU  - Chen,Jun
AU  - Xavier,Sandhya
AU  - Moskowitz-Kassai,Eliza
AU  - Chen,Robert
AU  - Lu,Connie Y
AU  - Sanduski,Kyle
AU  - Špes,Aleš
AU  - Turk,Boris
AU  - Goligorsky,Michael S
TI  - Cathepsin cleavage of sirtuin 1 in endothelial progenitor cells mediates stress-induced premature senescence
SN  - 1525-2191
PY  - 2012///0427
KW  - Animals
KW  - Apoptosis
KW  - drug effects
KW  - Arginine
KW  - analogs & derivatives
KW  - Autophagy
KW  - Azoles
KW  - pharmacology
KW  - Cardiovascular Diseases
KW  - etiology
KW  - Cathepsins
KW  - Cell Membrane Permeability
KW  - physiology
KW  - Cells, Cultured
KW  - Cellular Senescence
KW  - Collagen Type I
KW  - Down-Regulation
KW  - Endothelial Cells
KW  - Endothelium, Vascular
KW  - Hydrogen Peroxide
KW  - Isoindoles
KW  - Lysosomes
KW  - metabolism
KW  - Mice
KW  - Mice, Knockout
KW  - Mice, Transgenic
KW  - Organoselenium Compounds
KW  - Recombinant Proteins
KW  - Risk Factors
KW  - Sirtuin 1
KW  - deficiency
KW  - Stem Cells
KW  - Stress, Physiological
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1016/j.ajpath.2011.11.033
ER  -