Chen, Jun

Cathepsin cleavage of sirtuin 1 in endothelial progenitor cells mediates stress-induced premature senescence. [electronic resource] - The American journal of pathology Mar 2012 - 973-983 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1525-2191

10.1016/j.ajpath.2011.11.033 doi


Animals
Apoptosis--drug effects
Arginine--analogs & derivatives
Autophagy--drug effects
Azoles--pharmacology
Cardiovascular Diseases--etiology
Cathepsins--pharmacology
Cell Membrane Permeability--physiology
Cells, Cultured
Cellular Senescence--drug effects
Collagen Type I--pharmacology
Down-Regulation
Endothelial Cells--drug effects
Endothelium, Vascular
Hydrogen Peroxide--pharmacology
Isoindoles
Lysosomes--metabolism
Mice
Mice, Knockout
Mice, Transgenic
Organoselenium Compounds--pharmacology
Recombinant Proteins
Risk Factors
Sirtuin 1--deficiency
Stem Cells--drug effects
Stress, Physiological--drug effects