TY - GEN AU - Ruiz-Heiland,Gisela AU - Horn,Angelika AU - Zerr,Pawel AU - Hofstetter,Willy AU - Baum,Wolfgang AU - Stock,Michael AU - Distler,Jörg H AU - Nimmerjahn,Falk AU - Schett,Georg AU - Zwerina,Jochen TI - Blockade of the hedgehog pathway inhibits osteophyte formation in arthritis SN - 1468-2060 PY - 2012///0402 KW - Animals KW - Arthritis, Experimental KW - complications KW - Biphenyl Compounds KW - pharmacology KW - Bone and Bones KW - metabolism KW - Cartilage, Articular KW - Cell Differentiation KW - genetics KW - Chondrocytes KW - pathology KW - Drug Evaluation, Preclinical KW - methods KW - Hedgehog Proteins KW - antagonists & inhibitors KW - Hypertrophy KW - Male KW - Mice KW - Mice, Inbred C57BL KW - Microscopy, Fluorescence KW - Osteoblasts KW - Osteophyte KW - etiology KW - Periosteum KW - Receptors, G-Protein-Coupled KW - Signal Transduction KW - drug effects KW - Smoothened Receptor KW - Up-Regulation N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1136/ard.2010.148262 ER -