Ruiz-Heiland, Gisela <br/><br/>
Blockade of the hedgehog pathway inhibits osteophyte formation in arthritis.  [electronic resource] 

 -  Annals of the rheumatic diseases  Mar 2012 
 - 400-7 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1468-2060 
<br/><br/><label>Standard No.: </label>10.1136/ard.2010.148262  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Arthritis, Experimental--complications<br/>Biphenyl Compounds--pharmacology<br/>Bone and Bones--metabolism<br/>Cartilage, Articular--metabolism<br/>Cell Differentiation--genetics<br/>Chondrocytes--pathology<br/>Drug Evaluation, Preclinical--methods<br/>Hedgehog Proteins--antagonists & inhibitors<br/>Hypertrophy<br/>Male<br/>Mice<br/>Mice, Inbred C57BL<br/>Microscopy, Fluorescence<br/>Osteoblasts--pathology<br/>Osteophyte--etiology<br/>Periosteum--pathology<br/>Receptors, G-Protein-Coupled--antagonists & inhibitors<br/>Signal Transduction--drug effects<br/>Smoothened Receptor<br/>Up-Regulation--drug effects