TY - GEN AU - Gupta,Pankaj AU - Alvey,Christine AU - Wang,Rong AU - Dowty,Martin E AU - Fahmi,Odette A AU - Walsky,Robert L AU - Riese,Richard J AU - Krishnaswami,Sriram TI - Lack of effect of tofacitinib (CP-690,550) on the pharmacokinetics of the CYP3A4 substrate midazolam in healthy volunteers: confirmation of in vitro data SN - 1365-2125 PY - 2012///1119 KW - Adult KW - Cross-Over Studies KW - Cytochrome P-450 CYP3A KW - metabolism KW - Drug Interactions KW - Female KW - GABA Modulators KW - pharmacokinetics KW - Half-Life KW - Humans KW - Janus Kinases KW - antagonists & inhibitors KW - Male KW - Metabolic Clearance Rate KW - Midazolam KW - Middle Aged KW - Piperidines KW - Pyrimidines KW - pharmacology KW - Pyrroles KW - Young Adult N1 - Publication Type: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1111/j.1365-2125.2012.04168.x ER -