TY - GEN AU - Liu,Wenzhong AU - Singh,Rajvir AU - Choi,Cheol Soo AU - Lee,Hui-Young AU - Keramati,Ali R AU - Samuel,Varman T AU - Lifton,Richard P AU - Shulman,Gerald I AU - Mani,Arya TI - Low density lipoprotein (LDL) receptor-related protein 6 (LRP6) regulates body fat and glucose homeostasis by modulating nutrient sensing pathways and mitochondrial energy expenditure SN - 1083-351X PY - 2012///0424 KW - Adipose Tissue, Brown KW - metabolism KW - Adiposity KW - physiology KW - Alleles KW - Animals KW - Diabetes Mellitus, Type 2 KW - chemically induced KW - Dietary Fats KW - adverse effects KW - Energy Metabolism KW - drug effects KW - Forkhead Box Protein O1 KW - Forkhead Transcription Factors KW - genetics KW - Gluconeogenesis KW - Glucose KW - Glucose-6-Phosphatase KW - Homeostasis KW - Insulin Resistance KW - Low Density Lipoprotein Receptor-Related Protein-6 KW - Mechanistic Target of Rapamycin Complex 1 KW - Mice KW - Mice, Knockout KW - Mitochondria KW - Multiprotein Complexes KW - Obesity KW - Proteins KW - Receptors, Leptin KW - TOR Serine-Threonine Kinases KW - Wnt Signaling Pathway N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1074/jbc.M111.286724 ER -