TY  - GEN
AU  - Lanner,Johanna T
AU  - Georgiou,Dimitra K
AU  - Dagnino-Acosta,Adan
AU  - Ainbinder,Alina
AU  - Cheng,Qing
AU  - Joshi,Aditya D
AU  - Chen,Zanwen
AU  - Yarotskyy,Viktor
AU  - Oakes,Joshua M
AU  - Lee,Chang Seok
AU  - Monroe,Tanner O
AU  - Santillan,Arturo
AU  - Dong,Keke
AU  - Goodyear,Laurie
AU  - Ismailov,Iskander I
AU  - Rodney,George G
AU  - Dirksen,Robert T
AU  - Hamilton,Susan L
TI  - AICAR prevents heat-induced sudden death in RyR1 mutant mice independent of AMPK activation
SN  - 1546-170X
PY  - 2012///0329
KW  - AMP-Activated Protein Kinases
KW  - metabolism
KW  - Adenosine Triphosphate
KW  - Aminoimidazole Carboxamide
KW  - analogs & derivatives
KW  - Animals
KW  - Calcium
KW  - Death, Sudden
KW  - prevention & control
KW  - Enzyme Activation
KW  - Heat Stress Disorders
KW  - genetics
KW  - Hot Temperature
KW  - adverse effects
KW  - Male
KW  - Mice
KW  - Mice, Mutant Strains
KW  - Mice, Transgenic
KW  - Muscle, Skeletal
KW  - drug effects
KW  - Reactive Nitrogen Species
KW  - Reactive Oxygen Species
KW  - Ribonucleotides
KW  - pharmacology
KW  - Ryanodine Receptor Calcium Release Channel
KW  - Sarcoplasmic Reticulum
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S
UR  - https://doi.org/10.1038/nm.2598
ER  -