Lanner, Johanna T <br/><br/>
AICAR prevents heat-induced sudden death in RyR1 mutant mice independent of AMPK activation.  [electronic resource] 

 -  Nature medicine  Jan 2012 
 - 244-51 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S. 
<br/><br/><label>ISSN: </label>1546-170X 
<br/><br/><label>Standard No.: </label>10.1038/nm.2598  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>AMP-Activated Protein Kinases--metabolism<br/>Adenosine Triphosphate--metabolism<br/>Aminoimidazole Carboxamide--analogs & derivatives<br/>Animals<br/>Calcium--metabolism<br/>Death, Sudden--prevention & control<br/>Enzyme Activation<br/>Heat Stress Disorders--genetics<br/>Hot Temperature--adverse effects<br/>Male<br/>Mice<br/>Mice, Mutant Strains<br/>Mice, Transgenic<br/>Muscle, Skeletal--drug effects<br/>Reactive Nitrogen Species--metabolism<br/>Reactive Oxygen Species--metabolism<br/>Ribonucleotides--pharmacology<br/>Ryanodine Receptor Calcium Release Channel--drug effects<br/>Sarcoplasmic Reticulum--drug effects