TY  - GEN
AU  - Tian,Wang
AU  - Han,Xiaofeng
AU  - Yan,Maocai
AU  - Xu,Yan
AU  - Duggineni,Srinivas
AU  - Lin,Nan
AU  - Luo,Guifen
AU  - Li,Yan Michael
AU  - Han,Xiaobing
AU  - Huang,Ziwei
AU  - An,Jing
TI  - Structure-based discovery of a novel inhibitor targeting the β-catenin/Tcf4 interaction
SN  - 1520-4995
PY  - 2012///0307
KW  - Antineoplastic Agents
KW  - pharmacology
KW  - Basic Helix-Loop-Helix Leucine Zipper Transcription Factors
KW  - chemistry
KW  - Basic Helix-Loop-Helix Transcription Factors
KW  - metabolism
KW  - Cell Proliferation
KW  - drug effects
KW  - Cell Survival
KW  - Crystallography, X-Ray
KW  - Down-Regulation
KW  - Drug Evaluation, Preclinical
KW  - methods
KW  - HCT116 Cells
KW  - Humans
KW  - Models, Molecular
KW  - Protein Binding
KW  - Protein Conformation
KW  - Small Molecule Libraries
KW  - Transcription Factor 4
KW  - Transcription Factors
KW  - Transcription, Genetic
KW  - User-Computer Interface
KW  - Wnt Signaling Pathway
KW  - beta Catenin
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1021/bi201428h
ER  -