Georgiou, Kristen R

Deregulation of the CXCL12/CXCR4 axis in methotrexate chemotherapy-induced damage and recovery of the bone marrow microenvironment. [electronic resource] - International journal of experimental pathology Apr 2012 - 104-14 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1365-2613

10.1111/j.1365-2613.2011.00800.x doi


Animals
Antineoplastic Agents--adverse effects
Bone Marrow Cells--drug effects
Cell Count
Cell Lineage
Cellular Microenvironment--drug effects
Chemokine CXCL12--genetics
Colony-Forming Units Assay
Gene Expression Regulation, Neoplastic--drug effects
Matrix Metalloproteinase 9--metabolism
Methotrexate--adverse effects
Myeloid Progenitor Cells--drug effects
RNA, Messenger--metabolism
Rats
Rats, Sprague-Dawley
Real-Time Polymerase Chain Reaction
Receptors, CXCR4--genetics
Recombinant Proteins
Signal Transduction--drug effects
Tissue Inhibitor of Metalloproteinase-1--metabolism