McDonel, Patrick

Sin3a is essential for the genome integrity and viability of pluripotent cells. [electronic resource] - Developmental biology Mar 2012 - 62-73 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1095-564X

10.1016/j.ydbio.2011.12.019 doi


Animals
Apoptosis--genetics
Blotting, Western
Cell Cycle Checkpoints--genetics
Cell Survival--genetics
Cells, Cultured
DNA Damage
E2F Transcription Factors--genetics
Embryo, Mammalian--cytology
Embryonic Stem Cells--metabolism
Female
Flow Cytometry
G2 Phase--genetics
Gene Expression Regulation, Developmental
Genomic Instability--genetics
Germ Layers--cytology
Male
Mice
Mice, 129 Strain
Mice, Inbred C57BL
Mice, Knockout
Pluripotent Stem Cells--metabolism
Proto-Oncogene Proteins c-myc--genetics
Repressor Proteins--genetics
Reverse Transcriptase Polymerase Chain Reaction
Sin3 Histone Deacetylase and Corepressor Complex