TY  - GEN
AU  - Montano,Ryan
AU  - Chung,Injae
AU  - Garner,Kristen M
AU  - Parry,David
AU  - Eastman,Alan
TI  - Preclinical development of the novel Chk1 inhibitor SCH900776 in combination with DNA-damaging agents and antimetabolites
SN  - 1538-8514
PY  - 2012///0618
KW  - Antimetabolites
KW  - pharmacology
KW  - Antineoplastic Agents
KW  - Blotting, Western
KW  - Camptothecin
KW  - analogs & derivatives
KW  - Cell Cycle Checkpoints
KW  - drug effects
KW  - Cell Line
KW  - Cell Line, Tumor
KW  - Cell Proliferation
KW  - Cell Survival
KW  - Checkpoint Kinase 1
KW  - Cytarabine
KW  - DNA Breaks, Double-Stranded
KW  - DNA Damage
KW  - Deoxycytidine
KW  - Dose-Response Relationship, Drug
KW  - Drug Screening Assays, Antitumor
KW  - Drug Synergism
KW  - Flow Cytometry
KW  - Humans
KW  - Hydroxyurea
KW  - Irinotecan
KW  - Molecular Structure
KW  - Phosphorylation
KW  - Protein Kinase Inhibitors
KW  - chemistry
KW  - Protein Kinases
KW  - metabolism
KW  - Pyrazoles
KW  - Pyrimidines
KW  - Staurosporine
KW  - Gemcitabine
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural
UR  - https://doi.org/10.1158/1535-7163.MCT-11-0406
ER  -