Lack of efficacy of curcumin on neurodegeneration in the mouse model of Niemann-Pick C1. [electronic resource]
- Pharmacology, biochemistry, and behavior Mar 2012
- 125-31 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1873-5177
10.1016/j.pbb.2011.12.009 doi
Aging--physiology Animals Avoidance Learning--drug effects Carrier Proteins--genetics Chromatography, High Pressure Liquid Curcumin--therapeutic use Diet Intracellular Signaling Peptides and Proteins Lipids--pharmacology Mass Spectrometry Membrane Glycoproteins--genetics Memory--drug effects Mice Mice, Inbred BALB C Mice, Knockout Motor Activity--drug effects Nerve Degeneration--drug therapy Niemann-Pick C1 Protein Niemann-Pick Disease, Type C--drug therapy Pharmaceutical Vehicles--pharmacology Phosphatidylcholines--pharmacology Polymerase Chain Reaction Postural Balance--drug effects Stearic Acids--pharmacology Survival