TY  - GEN
AU  - Montaseri,Azadeh
AU  - Busch,Franziska
AU  - Mobasheri,Ali
AU  - Buhrmann,Constanze
AU  - Aldinger,Constance
AU  - Rad,Jafar Soleimani
AU  - Shakibaei,Mehdi
TI  - IGF-1 and PDGF-bb suppress IL-1β-induced cartilage degradation through down-regulation of NF-κB signaling: involvement of Src/PI-3K/AKT pathway
SN  - 1932-6203
PY  - 2012///0827
KW  - Animals
KW  - Apoptosis
KW  - drug effects
KW  - Becaplermin
KW  - Cartilage
KW  - Cell Differentiation
KW  - Cells, Cultured
KW  - Chondrocytes
KW  - Collagen Type II
KW  - metabolism
KW  - Dogs
KW  - Down-Regulation
KW  - Enzyme Activation
KW  - Extracellular Matrix
KW  - Extracellular Signal-Regulated MAP Kinases
KW  - I-kappa B Proteins
KW  - Imidazoles
KW  - pharmacology
KW  - Insulin-Like Growth Factor I
KW  - Integrin beta1
KW  - Interleukin-1beta
KW  - NF-KappaB Inhibitor alpha
KW  - NF-kappa B
KW  - Phosphatidylinositol 3-Kinases
KW  - Phosphorylation
KW  - Proto-Oncogene Proteins c-akt
KW  - Proto-Oncogene Proteins c-sis
KW  - Quinoxalines
KW  - SOX9 Transcription Factor
KW  - Shc Signaling Adaptor Proteins
KW  - Signal Transduction
KW  - src-Family Kinases
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1371/journal.pone.0028663
ER  -