TY - GEN AU - Chen,Qi AU - Prior,Marguerite AU - Dargusch,Richard AU - Roberts,Amanda AU - Riek,Roland AU - Eichmann,Cédric AU - Chiruta,Chandramouli AU - Akaishi,Tatsuhiro AU - Abe,Kazuho AU - Maher,Pamela AU - Schubert,David TI - A novel neurotrophic drug for cognitive enhancement and Alzheimer's disease SN - 1932-6203 PY - 2012///0827 KW - Alzheimer Disease KW - drug therapy KW - Amyloid beta-Peptides KW - metabolism KW - Animals KW - Behavior, Animal KW - drug effects KW - Brain-Derived Neurotrophic Factor KW - Cognition KW - Curcumin KW - analogs & derivatives KW - Disease Models, Animal KW - Heat-Shock Proteins KW - Hippocampus KW - Humans KW - Immunohistochemistry KW - Inflammation KW - pathology KW - Long-Term Potentiation KW - Memory KW - Mice KW - Nerve Growth Factors KW - pharmacology KW - Neuroprotective Agents KW - chemistry KW - Oxidants KW - Oxidative Stress KW - Phosphorylation KW - Pyrazoles KW - Rats KW - Solubility KW - Structure-Activity Relationship KW - Synapses KW - Up-Regulation N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1371/journal.pone.0027865 ER -