TY - GEN AU - Aso,Ester AU - Lomoio,Selene AU - López-González,Irene AU - Joda,Laura AU - Carmona,Margarita AU - Fernández-Yagüe,Núria AU - Moreno,Jesús AU - Juvés,Salvador AU - Pujol,Aurora AU - Pamplona,Reinald AU - Portero-Otin,Manuel AU - Martín,Virginia AU - Díaz,Mario AU - Ferrer,Isidro TI - Amyloid generation and dysfunctional immunoproteasome activation with disease progression in animal model of familial Alzheimer's disease SN - 1750-3639 PY - 2013///0424 KW - Age Factors KW - Alzheimer Disease KW - complications KW - Amyloid beta-Peptides KW - metabolism KW - Amyloid beta-Protein Precursor KW - genetics KW - Animals KW - Aspartic Acid Endopeptidases KW - Avoidance Learning KW - physiology KW - Brain KW - Cognition Disorders KW - etiology KW - Cysteine Endopeptidases KW - Disease Models, Animal KW - Disease Progression KW - Gene Expression Regulation KW - Humans KW - Mice KW - Mice, Inbred C57BL KW - Mice, Transgenic KW - Microscopy, Electron, Transmission KW - Microscopy, Immunoelectron KW - Mitogen-Activated Protein Kinases KW - Mutation KW - Neuropsychological Tests KW - Plaque, Amyloid KW - Presenilin-1 KW - Proteasome Endopeptidase Complex KW - RNA, Messenger KW - Recognition, Psychology KW - Signal Transduction KW - Superoxide Dismutase KW - Superoxide Dismutase-1 KW - Ubiquitin Thiolesterase KW - alpha-Synuclein KW - tau Proteins N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1111/j.1750-3639.2011.00560.x ER -