Development of pulmonary arterial hypertension in mice over-expressing S100A4/Mts1 is specific to females. [electronic resource]
- Respiratory research Dec 2011
- 159 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1465-993X
10.1186/1465-9921-12-159 doi
Analysis of Variance Animals Blood Pressure--genetics Blotting, Western Cell Proliferation Cells, Cultured Disease Models, Animal Estradiol--metabolism Familial Primary Pulmonary Hypertension Female Genetic Predisposition to Disease Hypertension, Pulmonary--genetics Hypertrophy, Right Ventricular--genetics Immunohistochemistry Male Mice Mice, Inbred C57BL Mice, Inbred CBA Mice, Transgenic Muscle, Smooth, Vascular--metabolism Myocytes, Smooth Muscle--metabolism Phenotype Pulmonary Artery--metabolism Real-Time Polymerase Chain Reaction Receptor for Advanced Glycation End Products Receptors, Immunologic--genetics Reverse Transcriptase Polymerase Chain Reaction S100 Calcium-Binding Protein A4 S100 Proteins--genetics Sex Factors Signal Transduction Up-Regulation Ventricular Function, Right Ventricular Pressure