TY  - GEN
AU  - Tai,Wei-Tien
AU  - Cheng,Ann-Lii
AU  - Shiau,Chung-Wai
AU  - Liu,Chun-Yu
AU  - Ko,Ching-Huai
AU  - Lin,Mai-Wei
AU  - Chen,Pei-Jer
AU  - Chen,Kuen-Feng
TI  - Dovitinib induces apoptosis and overcomes sorafenib resistance in hepatocellular carcinoma through SHP-1-mediated inhibition of STAT3
SN  - 1538-8514
PY  - 2012///0618
KW  - Animals
KW  - Apoptosis
KW  - drug effects
KW  - Benzenesulfonates
KW  - pharmacology
KW  - Benzimidazoles
KW  - chemistry
KW  - Blotting, Western
KW  - Carcinoma, Hepatocellular
KW  - drug therapy
KW  - Cell Line, Tumor
KW  - Dose-Response Relationship, Drug
KW  - Drug Resistance, Neoplasm
KW  - Humans
KW  - Liver Neoplasms
KW  - Male
KW  - Mice
KW  - Mice, Nude
KW  - Molecular Structure
KW  - Niacinamide
KW  - analogs & derivatives
KW  - Phenylurea Compounds
KW  - Protein Kinase Inhibitors
KW  - Protein Tyrosine Phosphatase, Non-Receptor Type 6
KW  - genetics
KW  - Pyridines
KW  - Quinolones
KW  - RNA Interference
KW  - STAT3 Transcription Factor
KW  - Sorafenib
KW  - Tumor Burden
KW  - Xenograft Model Antitumor Assays
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1158/1535-7163.MCT-11-0412
ER  -