Tai, Wei-Tien <br/><br/>
Dovitinib induces apoptosis and overcomes sorafenib resistance in hepatocellular carcinoma through SHP-1-mediated inhibition of STAT3.  [electronic resource] 

 -  Molecular cancer therapeutics  Feb 2012 
 - 452-63 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1538-8514 
<br/><br/><label>Standard No.: </label>10.1158/1535-7163.MCT-11-0412  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Apoptosis--drug effects<br/>Benzenesulfonates--pharmacology<br/>Benzimidazoles--chemistry<br/>Blotting, Western<br/>Carcinoma, Hepatocellular--drug therapy<br/>Cell Line, Tumor<br/>Dose-Response Relationship, Drug<br/>Drug Resistance, Neoplasm--drug effects<br/>Humans<br/>Liver Neoplasms--drug therapy<br/>Male<br/>Mice<br/>Mice, Nude<br/>Molecular Structure<br/>Niacinamide--analogs & derivatives<br/>Phenylurea Compounds<br/>Protein Kinase Inhibitors--chemistry<br/>Protein Tyrosine Phosphatase, Non-Receptor Type 6--genetics<br/>Pyridines--pharmacology<br/>Quinolones--chemistry<br/>RNA Interference<br/>STAT3 Transcription Factor--genetics<br/>Sorafenib<br/>Tumor Burden--drug effects<br/>Xenograft Model Antitumor Assays